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Chapter 1. Cell proliferation and apoptosis / Laura B. Pitzonka and David W. Goodrich -- chapter 2. Cancer stem cells / Sadhna Dhingra and Dongfeng Tan -- chapter 3. Cell signal transduction / Markus Morkel -- chapter 4. Oncogenes / Sadhna Dhingra and Dongfeng Tan -- chapter 5. Tumor suppressor genes / Markus Reschke, Lev M. Kats, and Pier Paolo Pandolfi -- chapter 6. Viruses and human cancers : pathogenesis and therapeutic implication / Ih-Jen Su, Yao Chang, Grace Yu, and Charles Dwo-Yuan Si -- chapter 7. Introduction to molecular techniques and instrumentation / Shengle Zhang and Dongfeng Tan -- chapter 8. Transcriptome analysis / Shengle Zhang -- chapter 9. Immunohistochemistry / Jeannelyn S. Estrella -- chapter 10. Cancer genomic sequencing / Yingfei Wei and Guo-Liang Yu -- chapter 11. Mass spectrometry : principles and applications in cancer diagnosis and management / Oliver J. Semmes, Richard R. Drake, and Julius O. Nyalwidhe -- chapter 12. Cancer proteomics / Kristin Huntoon and Zhengping Zhuang -- chapter 13. Morphoproteomics / Robert E. Brown and Jamie J. Buryanek -- chapter 14. Flow cytometry / George Deeb -- chapter 15. Cancer cytogenomics / Gary Lu -- chapter 16. DNA hypermethylation in cancer / Bin Yang -- chapter 17. Single nucleotide polymorphisms / Qingyi Wei -- chapter 18. Overview of molecular tests and personalized cancer medicine / Manuel Salto-Tellez -- chapter 19. Molecular screening, genetic counseling, and cancer prevention : Lynch syndrome as a model / Henry T. Lynch, Carrie L. Snyder, Jane F. Lynch, Stephen Lanspa, and Peter Silberstein -- chapter 20. Molecular imaging and cancer management : PET and MR agents for molecular imaging of cancer metabolism / Yunkou Wu, Xiankai Sun, and A. Dean Sherry -- chapter 21. Detection and molecular monitoring of minimal residual diseases in myeloid neoplasms / C. Cameron Yin -- chapter 22. Molecular assessment of cancer prognosis / Qing Zhao and Dongfeng Tan -- chapter. 23 Quality control, assurance, and standardization of molecular diagnostics / Matthew J. McGinniss, Ryan P. Bender, and Anatole Ghazalpour -- chapter 24. Biostatistics and bioinformatics / Qian Shi and Daniel J. Sargent -- chapter 25. In vitro companion diagnostic and anti-cancer Drug co-development : regulatory perspectives / Reena Philip, Elizabeth Mansfield, Lea Carrington, Yun-Fu Hu, and Maria Chan -- chapter 26. Molecular biology and pathology of lung cancer : genotype-morphology correlation / Yuichi Ishikawa and Osamu Matsubara -- chapter 27. Molecular diagnostics of breast cancer / Ping Tang and David G. Hicks -- chapter 28. Molecular diagnostics of colorectal cancer / Dongfeng Tan -- chapter 29. Molecular diagnostics of esophageal and gastric cancers / Wataru Yasui, Naohide Oue, Kazuhiro Sentani, and Dongfeng Tan -- chapter 30. Molecular biology of prostate cancer : practical considerations for diagnosis and prognosis / David G. Bostwick -- chapter 31. Molecular diagnostics of hepatocellular carcinoma / Seung Kew Yoon, Hyun Goo Woo, Dongfeng Tan, and Yoon Jun Kim -- chapter 32. Molecular diagnostics of pancreatic cancer / Marco Dal Molin and Anirban Maitra -- chapter 33. Molecular diagnostics of head and neck cancer / Adel K. El-Naggar -- chapter 34. Immunohistochemical and molecular diagnosis of melanoma / Andrea Suarez and Whitney A. High -- chapter 35. Molecular diagnostics of hematopoietic neoplasms / Qiulu Pan and Dan Jones -- chapter 36. Molecular diagnostics of lymphomas / Keila Rivera-Roman and Christopher D. Gocke -- chapter 37. Molecular diagnostics of gynecologic neoplasms / Robert J. Kurman, Christina M. Bagby, and Ie-Ming Shih -- chapter 38. Molecular diagnostics of bladder and kidney cancers / Hikmat A. Al-Ahmadie, Ying-Bei Chen, and Victor E. Reuter -- chapter 39. Molecular diagnosis of soft tissue sarcomas / Jorge Torres-Mora and Andre M. Oliveira -- chapter 40. Molecular diagnosis of glioma / Adriana Olar and Gregory N. Fuller -- chapter 41. Molecular diagnostics of pediatric neoplasms / Jennifer Picarsic, Marina Nikiforova, and Miguel Reyes-Mugica -- chapter 42. Molecular diagnostics of metastatic malignancies / Mikhail Lisovsky, Laura J. Tafe, and Joel A. Lefferts -- chapter 43. DNA repair and cancer therapeutics / Mark R. Kelley and Melissa L. Fishel -- chapter 44. Monoclonal antibodies for the treatment of cancer / Jason C. Steel, Brian J. Morrison, and John C. Morris -- chapter 45. Vaccines and cancer therapy / Joseph W. Kim and James L. Gulley -- chapter 46. Cancer gene therapy : nucleic acids as therapeutic agents / Richard A. Morgan and Daniel Abate-Daga -- chapter 47. Anti-angiogenesis therapy of cancer / Kun Guo and Keping Xie -- chapter 48. MicroRNAs and cancer therapeutics / Maitri Y. Shah and George A. Calin -- chapter 49. Molecular basis of cancer radiation treatment / Heath Skinner, Amit Deorukhkar, and Sunil Krishnan -- chapter 50. Nanotechnology and cancer therapy / Chun Li -- chapter 51. New approaches to integration of personalized medicine in early cancer drug development / Aik-Choon Tan, Stephen Leong, Todd M. Pitts, John J. Tentler, and S. Gail Eckhardt -- chapter 52. Personalized medicine and targeted therapy of lung cancer / Mary C. Pinder-Schenck and Scott J. Antonia -- chapter 53. Personalized medicine and targeted therapy of breast cancer / Komal Jhaveri, Chau Dang, and Clifford Hudis -- chapter 54. Personalized medicine and targeted therapy for colorectal cancer / Joleen M. Hubbard and Axel Grothey -- chapter 55. Personalized medicine and targeted therapy of esophageal cancer / Harry H. Yoon and Frank A. Sinicrope -- chapter 56. Personalized medicine and targeted therapy of gastric cancer / YingWei Xue, XueFeng Yu, and Yanqiao Zhang -- chapter 57. Personalized medicine and targeted therapy for prostate cancer / Madhuri Bajaj, Michael A. Carducci, and Elisabeth I. Heath -- chapter 58. Personalized medicine and targeted therapy of hepatocellular carcinoma / Jiang Hongchi, John W. Linford, and Ahmed O. Kaseb -- chapter 59. Personalized medicine and targeted therapy of pancreatic cancer : current status and proposed strategies / Milind Javle -- chapter 60. Personalized medicine and targeted therapy of neuroendocrine neoplasms / Jeana Garris and James C. Yao -- chapter 61. Personalized medicine and targeted therapy of head and neck cancer / Ronald Myint, Kathryn A. Gold, and Edward S. Kim -- chapter 62. Personalized medicine and targeted therapy for melanoma / Keith T. Flaherty -- chapter 63. Personalized medicine and targeted therapy of leukemia / Pavan Kumar Bhamidipati, Elias Jabbour, and Jorge Cortes -- chapter 64. Personalized medicine and targeted therapy of gynecologic cancers / Lainie P. Martin and Russell J. Schilder -- chapter 65. Personalized medicine and targeted therapy of renal cell carcinoma / C. Lance Cowey and Thomas E. Hutson -- chapter 66. Personalized medicine and targeted therapy of gliomas / Brett J. Theeler, John De Groot, and W.K. Alfred Yung -- chapter 67. Personalized medicine and targeted therapy for osteosarcoma / Jonathan Gill, David Geller, and Richard Gorlick -- chapter 68. Molecular basis of chemoradiotherapy and high-precision radiotherapy / Michio Yoshimura, Masahiro Hiraoka, and Hiroshi Harada -- chapter 69. New approaches to personalized medicine and targeted drug discovery / Garrett M. Dancik and Dan Theodorescu -- chapter 70. The future of molecular diagnostics in oncology / Michael C. Dugan and Dongfeng Tan. |