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Affinity and efficacy[electronic res...
Ehlert, Frederick J.

 

  • Affinity and efficacy[electronic resource] :the components of drug-receptor interactions /
  • 紀錄類型: 書目-語言資料,印刷品 : Monograph/item
    杜威分類號: 615.7/0452
    書名/作者: Affinity and efficacy : the components of drug-receptor interactions // Frederick J. Ehlert.
    其他題名: Components of drug-receptor interactions
    作者: Ehlert, Frederick J.
    出版者: New Jersey : : World Scientific,, 2014.
    面頁冊數: 1 online resource.
    標題: Drug receptors.
    標題: Drugs - Effectiveness.
    標題: Drug-nutrient interactions.
    標題: Pharmaceutical chemistry.
    標題: Receptors, Drug.
    標題: Ligand-Gated Ion Channels.
    標題: Protein Binding.
    標題: Radioligand Assay.
    標題: Receptors, G-Protein-Coupled.
    ISBN: 9789814324229
    ISBN: 9814324221
    書目註: Includes bibliographical references.
    內容註: Ligand-gated ion channels -- Affinity and efficacy of orthosteric ligands at ligand-gated ion channels -- Competitive interactions between orthostheric ligands at ligand-gated ion channels -- Analysis of allosteric interactions at ligand-gated ion channels -- G protein-coupled receptors and G protein signaling -- Affinity and efficacy of the agonist-receptor-G-protein interaction -- Estimating affinity and efficacy by reverse-engineering and response-clamp analysis -- Analysis of agonism and inverse agonism in signaling pathways that exhibit constitutive activity -- Analysis of ligand bias in receptor signaling through different G protein pathways -- Competitive interactions between orthosteric ligands in functional assays on G protein-coupled receptors -- Analysis of allosterism in functional assays on G protein-coupled receptors -- Analysis of drug-receptor interactions using radioligand binding assays on G protein-coupled receptors.
    電子資源: http://www.worldscientific.com/worldscibooks/10.1142/7888#t=toc
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