大葉大學圖書館 |

Circulating tumor cells[electronic resource] /

紀錄類型:	書目-語言資料,印刷品 : Monograph/item
杜威分類號:	616.99407
書名/作者:	Circulating tumor cells/ edited by Richard J. Cote, Ram H. Datar.
其他作者:	Cote, Richard J.
出版者:	New York, NY : : Springer New York :, 2016.
面頁冊數:	xxiv, 333 p. : : ill., digital ;; 24 cm.
Contained By:	Springer eBooks
標題:	Metastasis.
標題:	Cancer invasiveness.
標題:	Biomedicine.
標題:	Cancer Research.
ISBN:	9781493933631
ISBN:	9781493933617
內容註:	Preface -- Foreword -- Section I. Technologies for CTC Identification -- 1. Significance of Studying Circulating Tumor Cells -- 2. Affinity-Based Enrichment of Circulating Tumor Cells -- 3. Size-Based and Non-Affinity Based Microfluidic Devices for Circulating Tumor Cell Enrichment and Characterization -- 4. Molecular Assays for the Detection and Molecular Characterization of CTCs -- 5. Cancer Stem Cells and Circulating Tumor Cells Molecular Markers, Isolation Techniques and Clinical Implications -- Section II. Fundamental Studies of CTC -- 6. Circulating Tumor Cells and Tumor Dormancy -- 7. Prevention of Conversion of Tumor Dormancy into Proliferative Metastases -- 8. Genesis of Circulating Tumor Cells through Epithelial-Mesenchymal Transition as a Mechanism for Distant Dissemination -- Section III. CTC Analysis -- 9. CTC Analysis FISH, ISH, Array-CGH and Other Molecular Assays -- 10. Genome-Wide Gene Copy Number Analysis of Circulating Tumor Cells -- 11. Perspectives on the Functional Characterization and In Vitro Maintenance of Circulating Tumor Cells -- 12. Prognostic Implications of CTC in Breast Cancer -- Section IV. Potential Clinical Applications of CTC -- 13. CTC in Advanced Breast Cancer Prognosis, Monitoring and Clinical Utility -- 14. Evolution of Metastatic Disease: The Need for Monitoring and Emerging Therapeutic Opportunities -- 15. CTC for Biomarker and Companion Diagnostic Development -- 16. Perspectives on Clinical Applications of CTCs -- Index.
摘要、提要註:	This volume provides the latest research on circulating tumor cells aimed for cancer researchers, scientists, and molecular oncologists. It presents the basic concepts behind circulating tumor cells (CTCs), metastatic biology, and potential applications as to how CTCs can be used in diagnostic biomarkers. CTCs are cells that have detached from the primary tumor and circulate in the bloodstream. Such cells may become "seeds" for the growth of additional tumors. The field of analysis surrounding cancer metastasis has been steadily growing, and CTCs provide effective biomarkers that can be examined in peripheral blood through a minimally invasive "liquid biopsy" procedure. CTCs offer several exciting applications, not only as markers of disease progression but also as biomarkers of monitoring response to therapy and companion diagnostics for novel anticancer drug development.There has been rapid progress in the field, fueled by research in basic science, biomedical engineering, and clinical applications. This book presents the latest developments from world-wide leaders, and will be useful for anyone interested in this important and expanding field.
電子資源:	http://dx.doi.org/10.1007/978-1-4939-3363-1

Circulating tumor cells[electronic resource] /
Circulating tumor cells[electronic resource] /edited by Richard J. Cote, Ram H. Datar. - New York, NY :Springer New York :2016. - xxiv, 333 p. :ill., digital ;24 cm. - Current cancer research,2199-2584. - Current cancer research..

Preface -- Foreword -- Section I. Technologies for CTC Identification -- 1. Significance of Studying Circulating Tumor Cells -- 2. Affinity-Based Enrichment of Circulating Tumor Cells -- 3. Size-Based and Non-Affinity Based Microfluidic Devices for Circulating Tumor Cell Enrichment and Characterization -- 4. Molecular Assays for the Detection and Molecular Characterization of CTCs -- 5. Cancer Stem Cells and Circulating Tumor Cells Molecular Markers, Isolation Techniques and Clinical Implications -- Section II. Fundamental Studies of CTC -- 6. Circulating Tumor Cells and Tumor Dormancy -- 7. Prevention of Conversion of Tumor Dormancy into Proliferative Metastases -- 8. Genesis of Circulating Tumor Cells through Epithelial-Mesenchymal Transition as a Mechanism for Distant Dissemination -- Section III. CTC Analysis -- 9. CTC Analysis FISH, ISH, Array-CGH and Other Molecular Assays -- 10. Genome-Wide Gene Copy Number Analysis of Circulating Tumor Cells -- 11. Perspectives on the Functional Characterization and In Vitro Maintenance of Circulating Tumor Cells -- 12. Prognostic Implications of CTC in Breast Cancer -- Section IV. Potential Clinical Applications of CTC -- 13. CTC in Advanced Breast Cancer Prognosis, Monitoring and Clinical Utility -- 14. Evolution of Metastatic Disease: The Need for Monitoring and Emerging Therapeutic Opportunities -- 15. CTC for Biomarker and Companion Diagnostic Development -- 16. Perspectives on Clinical Applications of CTCs -- Index.

This volume provides the latest research on circulating tumor cells aimed for cancer researchers, scientists, and molecular oncologists. It presents the basic concepts behind circulating tumor cells (CTCs), metastatic biology, and potential applications as to how CTCs can be used in diagnostic biomarkers. CTCs are cells that have detached from the primary tumor and circulate in the bloodstream. Such cells may become "seeds" for the growth of additional tumors. The field of analysis surrounding cancer metastasis has been steadily growing, and CTCs provide effective biomarkers that can be examined in peripheral blood through a minimally invasive "liquid biopsy" procedure. CTCs offer several exciting applications, not only as markers of disease progression but also as biomarkers of monitoring response to therapy and companion diagnostics for novel anticancer drug development.There has been rapid progress in the field, fueled by research in basic science, biomedical engineering, and clinical applications. This book presents the latest developments from world-wide leaders, and will be useful for anyone interested in this important and expanding field.

ISBN: 9781493933631

Standard No.: 10.1007/978-1-4939-3363-1doiSubjects--Topical Terms:

388424
Metastasis.

LC Class. No.: RC269.5

Dewey Class. No.: 616.99407

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520 $a This volume provides the latest research on circulating tumor cells aimed for cancer researchers, scientists, and molecular oncologists. It presents the basic concepts behind circulating tumor cells (CTCs), metastatic biology, and potential applications as to how CTCs can be used in diagnostic biomarkers. CTCs are cells that have detached from the primary tumor and circulate in the bloodstream. Such cells may become "seeds" for the growth of additional tumors. The field of analysis surrounding cancer metastasis has been steadily growing, and CTCs provide effective biomarkers that can be examined in peripheral blood through a minimally invasive "liquid biopsy" procedure. CTCs offer several exciting applications, not only as markers of disease progression but also as biomarkers of monitoring response to therapy and companion diagnostics for novel anticancer drug development.There has been rapid progress in the field, fueled by research in basic science, biomedical engineering, and clinical applications. This book presents the latest developments from world-wide leaders, and will be useful for anyone interested in this important and expanding field.
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