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Antigenic variation[electronic resou...
Craig, Alister G.

 

  • Antigenic variation[electronic resource] /
  • 紀錄類型: 書目-語言資料,印刷品 : Monograph/item
    杜威分類號: 571.9645
    書名/作者: Antigenic variation/ edited by Alister Craig, Artur Scherf.
    其他作者: Craig, Alister G.
    出版者: London ; : Academic Press,, c2003.
    面頁冊數: xvi, 443 p. : : ill. ;; 24 cm.
    標題: Antigenic Variation - genetics.
    標題: Antigenic Variation - immunology.
    標題: Antigenic Variation - physiology.
    標題: Antigens.
    標題: Variation (Biology)
    ISBN: 9780121948511
    ISBN: 012194851X
    書目註: Includes bibliographical references and index.
    內容註: Synthesis of allelic/antigenic variation -- HIV variation -- a question of signal-to-noise -- Calicivirus -- Influenza, the chameleon virus -- Rotaviruses -- Mycoplasma -- Haemophilus Influenzae -- Phase Variation in Helicobacter pylori Lipopolysaccharide -- Genetic Variation in the Pathogenic Neisseria Species -- Candida Albicans -- The MSG Gene Family and Antigenic Variation in the Fungus P. carinii -- Trypanosome Antigenic Variation -- a heavy investment in the evasion of immunity -- Antigenic variation in Anaplasma marginale and Ehrlichia (Cowdria) ruminantium -- Antigenic Variation and its' Significance to Babsesia -- Antigenic Variation in Plasmodium falciparum and other Plasmodium -- Species -- Antigenic Variation in Borrelia: Relapsing Fever and Lyme Borreliosis -- Surface Antigenic Variation in Giardia lamblia -- Free-living and Parasitic Ciliates:The Impact of Antigenic Variation on Pathogen Population Structure, Fitness and Dynamics.
    摘要、提要註: The topic of antigenic variation is important in both biology and medicine. It is of enormous interest, as it describes the process(es) whereby microorganisms 'shift shape', by genetic rearrangement or otherwise. In medical terms, this has a major impact on the infectious disease process, since the immune system has great difficulty in keeping up with this variation, and thus eliminating the infectious agent. Antigenic variation is a major method by which microbes evade the immune response, and persist in the body. The broad scope of the book appeals to all those working in the field of infectious disease, immunology of infection, pathogenesis, molecular biology and also to evolutionary biologists. Topics covered include not only bacterial species, and viruses such as influenza, HIV, Rotavirus, but also eukaryotic parasites - one of the most fascinating groups of organisms exhibiting this behaviour. Comprehensive coverage of antigenic variation from viruses to parasites Discussions devoted to molecular mechanisms of host evasion Detailed descriptions of host/pathogen interactions.
    電子資源: An electronic book accessible through the World Wide Web; click for information
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