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Origin and evolution of viruses[elec...
Domingo, Esteban.

 

  • Origin and evolution of viruses[electronic resource].
  • 紀錄類型: 書目-語言資料,印刷品 : Monograph/item
    杜威分類號: 579.2138
    書名/作者: Origin and evolution of viruses
    其他作者: Domingo, Esteban.
    出版者: Amsterdam ; : Elsevier Academic Press,, c2008.
    面頁冊數: xii, 533 p., [24] p. of plates : : ill. (some col.) ;; 26 cm.
    附註: Previous ed.: 1999.
    標題: Viruses - Evolution.
    標題: Viruses - genetics.
    標題: Evolution.
    標題: Evolution, Molecular.
    標題: Adaptation, Physiological.
    標題: Virus Diseases.
    ISBN: 9780123741530
    ISBN: 012374153X
    書目註: Includes bibliographical references and index.
    內容註: Origins and widespread evolutionary significance of viruses; Nature and evolution of early replicons; Structure and evolution of viroids; Mutation, competition and selection as measured with small RNA molecules; Viral quasispecies, fitness variations and error;Phylogenetic analysis of viral sequences: principles and applications; Evolution of functional protein motifs in RNA viruses; Copying fidelity of viral and cellular polymerases; RNA interference and its evolutionary implications; Phage models of virus adaptation and evolution; Genomic analysis and evolution of large bacteriophages; Plant virus evolution: past, present and future; Mutant clouds and bottleneck events in plant virus evolution; Retrovirus evolution and pathogenesis; HIV population dynamics and drug treatments; The impact of rapid evolution of hepatitis viruses; Evolution of animal and human influenza viruses; Evolution and emergence of arboviruses; Parvovirus variation and evolution: impact on disease emergence; Genome diversity and evolution of human papillomaviruses; Poxvirus diversity and evolution; The molecular evolutionary history of the herpesviruses; Cellular functions involved in virual hypermutagenesis.
    摘要、提要註: New viral diseases are emerging continuously. Viruses adapt to new environments at astounding rates. Genetic variability of viruses jeopardizes vaccine efficacy. For many viruses mutants resistant to antiviral agents or host immune responses arise readily, for example, with HIV and influenza.These variations are all of utmost importance for human and animal health as they have prevented us from controlling these epidemic pathogens. This book focuses on the mechanisms that viruses use to evolve, survive and cause disease in their hosts. Covering human, animal, plant and bacterial viruses, it provides both the basic foundations for the evolutionary dynamics of viruses and specific examples of emerging diseases explained by the evolutionary flexibility of the viral agents that circulate in a continuously changing earth environment. * NEW to this edition - chapters on the molecular basis of copying fidelity of viral polymerases, methods to establish phylogenetic relationships among viruses, and the mechanisms of cellular RNA interference and editing functions as they affect virus evolution. * UNIQUE - combines theoretical concepts in evolution with detailed analyses of the evolution of important virus groups. * Bacterial, plant, animal and human viruses are compared regarding their interaction with their hosts.
    電子資源: An electronic book accessible through the World Wide Web; click for information
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